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Postpartum Depression Co-Occurring With Lactation-Related Osteoporosis

Received November 6, 2007; accepted February 6, 2008. From the Dept. of Psychiatry, Sisli Etfal Teaching and Research Hospital, Istanbul, Turkey; the Dept. of Obstetrics and Gynecology, Florence Nightingale Metropolitan Hospital, Bilim University School of Medicine, Istanbul, Turkey; and the Dept. of Orthopedic Surgery, Florence Nightingale Hospital, Bilim University School of Medicine, Istanbul, Turkey. Send correspondence and reprint requests to Basak Ozcelik, M.D., Dept. of Psychiatry, Sisli Etfal Teaching and Research Hospital, Istanbul, Turkey. e-mail: basakaykan{at}ttmail.com
© 2009 The Academy of Psychosomatic Medicine

BACKGROUND: Postpartum depression may present with somatic complaints. However, all somatic symptoms do not indicate a possible depression diagnosis. One of the clinical pictures related to physical complaints is osteoporosis in late pregnancy and lactation (PLO); this is a rare disorder, and its pathophysiology remains unknown. OBJECTIVE: The authors report here a case of PLO and depression in a 35-year-old primiparous patient with acute low back pain and postpartum depression 4 weeks after caesarean section. METHOD: Diagnosis was made by DXA scan and magnetic resonance imaging. Depression was assessed with the Edinburgh Postnatal Depression Scale. RESULTS: The patient achieved pain relief through treatment with calcium, vitamin D, calcitonin, weekly alendronate, and venlafaxine for depression. CONCLUSION: PLO and depression may have a common etiopathogenesis that needs further investigation.

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