Psychosomatics
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Psychosomatics 49:447-449, September-October 2008
doi: 10.1176/appi.psy.49.5.447
© 2008 Academy of Psychosomatic Medicine
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Case Report

Onset of Mania After CPAP in a Man With Obstructive Sleep Apnea

D. Bergé, M.D., P. Salgado, M.D., A. Rodríguez, M.D., and A. Bulbena, M.D., Ph.D.

Received November 23, 2006; revised April 17, 2007; accepted April 24, 2007. From Centre Forum Hospital del Mar, Institut d’Atenció Psiquiàtrica Salut Mental i Toxicomanies (IAPS). Send correspondence and reprint requests to Dr. Daniel Bergé, Centre Forum Hospital del Mar, C/ Llull 410, Barcelona, Spain 08019. e-mail: 94482{at}imas.imim.es
© 2008 The Academy of Psychosomatic Medicine

BACKGROUND: This short report presents the case of a man with chronic anergy and mild depressive symptoms probably due to obstructive sleep apnea (OAS). METHOD: The patient was treated with continuous positive airway pressure (CPAP). RESULT: He developed a first manic episode at an atypical age simultaneously with the beginning of treatment. DISCUSSION: Several possible connections between affective syndromes, OAS, and CPAP treatment are proposed and discussed relating to current literature.







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