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Antidepressant Treatment of Caregivers of Children With Asthma

Received September 15, 2006; revised November 21, 2006; accepted December 4, 2006. From the Depts. of Psychiatry, Pediatrics, and Internal Medicine, University of Texas Southwestern Medical Center at Dallas; and the Dept. of Psychiatry, School of Medicine and Biomedical Sciences, State University of New York at Buffalo. Send correspondence and reprint requests to E. Sherwood Brown, M.D., Ph.D., University of Texas Southwestern Medical Center 5323 Harry Hines Blvd., Dallas, TX 75390-8849. e-mail: Sherwood.Brown{at}UTSouthwestern.edu
© 2008 The Academy of Psychosomatic Medicine

BACKGROUND: Depression is common in caregivers of children with asthma and is associated with increased emergency service utilization for the child’s asthma. OBJECTIVE: This pilot study examined the impact of antidepressant treatment of depressed caregivers on the caregiver’s depression and the child’s asthma. METHOD: Eight depressed caregivers of children with asthma were given up to 6 months of algorithm-based antidepressant therapy. RESULTS: Caregiver depressive symptoms and the child’s asthma symptoms improved significantly. CONCLUSION: Unscheduled clinic visits showed a trend toward significant decrease. Larger trials are needed to confirm these findings and identify mechanisms linking improvement in caregiver depression with improvement in their child’s asthma.

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