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Risk Factors for Major Depressive Disorder and the Psychological Impact of Hysterectomy: A Prospective Investigation

Received April 20, 2006; revised August 15, 2006; accepted August 30, 2006. From the Dept. of Psychiatry, Kaohsiung Medical University Hospital, Taiwan. Send correspondence and reprint requests to Chih-Hung Ko, M.D., Dept. of Psychiatry, Kaohsiung Medical University Hospital, 100 Tzyou 1st Rd., Kaohsiung City, Taiwan 807. e-mail: cyberko{at}seed.net.tw
© 2008 The Academy of Psychosomatic Medicine

The authors prospectively evaluated the risk of major depressive disorder and the psychological impact of recent hysterectomy in 68 women who underwent hysterectomy for non-malignant conditions. Depression, anxiety, body image, sexual functioning, family support, life stress, and subjective gynecological symptoms were assessed 2 weeks before surgery and at 1 month and 4 months after surgery. Depression, anxiety, body image, and subjective gynecological symptoms improved after surgery; however, sexual functioning worsened after surgery. Previous emotional problems and poorer body image, sexual functioning, and higher stress 1 month after surgery are risk factors for post-hysterectomy major depressive disorder.

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