
Psychosomatics 48:412-417, October 2007
doi: 10.1176/appi.psy.48.5.412
© 2007 Academy of Psychosomatic Medicine
Cardiovascular Disease and Metabolic Risk Factors in Male Patients With Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder
Amy M. Kilbourne, Ph.D., M.P.H.,
Jaspreet S. Brar, M.D., M.P.H.,
Rebecca A. Drayer, M.D.,
Xiangyan Xu, M.S., and
Edward P. Post, M.D., Ph.D.
Received March 27, 2006; revised June 26, 2006; accepted July 10, 2006. From the VA Ann Arbor National Serious Mental Illness Treatment, Research, and Evaluation Center and the Depts. of Medicine and Psychiatry, Univ. of Michigan, Ann Arbor, MI; the Canandaigua VA Medical Center, Canandaigua, NY; the Univ. of Rochester School of Medicine and Dentistry, Rochester, NY; and the Dept. of Psychiatry, Univ. of Pittsburgh School of Medicine, Pittsburgh, PA. Send correspondence and reprint requests to Amy M. Kilbourne, Ph.D., M.P.H., VA Ann Arbor SMITREC (11H), 2215 Fuller Rd., Ann Arbor, MI 48105. e-mail: amykilbo{at}umich.edu
© 2007 The Academy of Psychosomatic Medicine
The authors determined whether diagnoses of cardiovascular disease (CVD) and CVD-related conditions differed by psychiatric diagnosis among male Veterans Administration patients from the mid-Atlantic region. Among 7,529 patients (mean age: 54.5 years), the prevalence of diagnoses ranged from 3.6% (stroke) to 35.4% (hypertension). Compared with schizophrenia patients, those with bipolar disorder were 19% more likely to have diabetes, 44% more likely to have coronary artery disease, and 18% more likely to have dyslipidemia, after adjustment. Clinical suspicion for CVD-related conditions, as well as risk-modification strategies, in patients with serious mental illness should incorporate differences in prevalence across specific psychiatric diagnoses.
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A. M. Kilbourne, E. P. Post, A. Nossek, L. Drill, S. Cooley, and M. S. Bauer
Improving Medical and Psychiatric Outcomes Among Individuals With Bipolar Disorder: A Randomized Controlled Trial
Psychiatr Serv,
July 1, 2008;
59(7):
760 - 768.
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