Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via Google Scholar Articles by Andrei, A. M. Articles by Wajngarten, M. Search for Related Content PubMed Citation Articles by Andrei, A. M. Articles by Wajngarten, M. Primary Care Depression

Major Depressive Disorder and Inflammatory Markers in Elderly Patients With Heart Failure

Received September 19, 2005; revised February 24, 2006; accepted March 8, 2006. From the Heart Institute, University of São Paulo School of Medicine, São Paulo, SP, Brazil; Massachusetts General Hospital, Department of Psychiatry, Boston, MA; Department and Institute of Psychiatry, University of São Paulo School of Medicine, São Paulo, SP, Brazil. Address correspondence and reprint requests to Dr. Fraguas. e-mail: rfraguas{at}partners.org
© 2007 The Academy of Psychosomatic Medicine

The authors evaluated levels of inflammatory markers in 34 chronic heart failure (CHF) out-patients age 65 years and over, with (N=18) and without (N=16) major depressive disorder (MDD), and healthy-control subjects (N=13). Patients with CHF had left-ventricular ejection fractions <0.40 and were in the New York Heart Association functional class II or III. The authors used the SCID DSM–IV to diagnosis MDD. High-sensitivity C-reactive protein levels were significantly higher in patients with CHF and MDD as compared with healthy-control subjects. No differences regarding tumor necrosis factor or interleukin₆ were found among the three groups.

Get information about faster international access.

Privacy Policy

Copyright © 2007 Academy of Psychosomatic Medicine. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us