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Negative Symptoms and HIV/AIDS Risk-Behavior Knowledge in Schizophrenia

Received December 21, 2005; revised March 13, 2006; accepted March 20, 2006. From the Ngaphakathi Workgroup, Dept. of Psychiatry, Univ. of Stellenbosch, Cape Town, South Africa. Send correspondence and reprint requests to Dr. Liezl Koen, P.O. Box 19063, Tygerberg 7505 South Africa. e-mail: psych{at}worldonline.co.za

Schizophrenia sufferers have been demonstrated to have relatively poor HIV/AIDS risk-behavior knowledge and, as a group, are found to be particularly vulnerable to contracting HIV. The authors asked whether an association could be demonstrated between specific symptoms and differing levels of knowledge. A structured clinical interview and HIV/AIDS Risk Questionnaires were administered to 102 subjects, and a principal-component analysis was performed for global and individual items, followed by comparisons between factors. Three factors (negative, positive, and global thought-disorder) emerged as significant between poor HIV/AIDS risk-behavior knowledge and higher negative-symptom scores. Findings support the notion that existing educational programs should be adapted to target specific areas of deficit.

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