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Age at Onset of Major Depression in Inner-City Adults With Asthma

Received May 11, 2005; revised October 13, 2005; accepted October 20, 2005. From the Dept. of Psychiatry and the Allergy and Immunology Division of the Dept. of Internal Medicine, Univ. of Texas Southwestern Medical Center, Dallas. Address correspondence and reprint requests to Dr. Brown, Dept. of Psychiatry, Univ. of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-8849. e-mail: sherwood.brown{at}utsouthwestern.edu

Depression generally begins before Type II diabetes and coronary artery disease; however, no data are available on whether asthma or major depressive disorder (MDD) have an earlier onset. The age at onset of asthma and depression were collected from 85 adult asthma patients with current MDD. The mean ages at onset of asthma and MDD were 21.0 years and 28.8 years, respectively. Asthma preceded MDD in 62% of cases; MDD preceded asthma onset in 24% of cases; and asthma and MDD had a concurrent onset in 14% of the cases. In asthma patients, unlike patients with Type II diabetes and coronary artery disease, depression appears generally to occur after the onset of asthma.

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