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Quality of Life in Patients With Chronic Obstructive Pulmonary Disease and Comorbid Anxiety or Depression

Received March 15, 2005; revised June 16, 2005; accepted August 9, 2005. From the Houston Center for Quality of Care and Utilization Studies, the Veterans Affairs HSR&D Center of Excellence, the Menninger Dept. of Psychiatry and Behavioral Sciences, the Section on Health Services Research, Dept. of Medicine, Baylor College of Medicine, Houston, TX, and the Veterans Affairs South Central Mental Illness Research, Education, & Clinical Center. Send correspondence and reprint requests to Jeffrey A. Cully, Ph.D., 2002 Holcombe (152), Houston, TX 77030. e-mail: jcully{at}bcm.tmc.edu
© 2006 The Academy of Psychosomatic Medicine

The authors examined 179 veterans with chronic obstructive pulmonary disease (COPD) to determine the relative contribution of clinical depression and/or anxiety (Beck Depression and Beck Anxiety Inventories) to their quality of life (Chronic Respiratory Questionnaire and Medical Outcomes Survey Short Form). Multiple-regression procedures found that both depression and anxiety were significantly related to negative quality-of-life outcomes (anxiety with both mental and physical health quality-of-life outcomes, and depression primarily with mental health). When comorbid with COPD, mental health symptoms of depression and anxiety are some of the most salient factors associated with quality-of-life outcomes.

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