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Psychosomatics 47:136-142, March-April 2006
doi: 10.1176/appi.psy.47.2.136
© 2006 Academy of Psychosomatic Medicine
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* Opioids
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Pain Medication Use Among Patients With Posttraumatic Stress Disorder

Ann C. Schwartz, M.D., Rebekah Bradley, Ph.D., Kristin M. Penza, Ph.D., Melissa Sexton, M.Div., Daniel Jay, M.D., Patrick J. Haggard, M.D., Steven J. Garlow, M.D., Ph.D., and Kerry J. Ressler, M.D., Ph.D.

Received November 7, 2004; revised May 29, 2005; accepted June 23, 2005. From the Dept. of Psychiatry and Behavioral Sciences, Emory Univ. School of Medicine, Atlanta, GA; the Dept. of Comparative Literature, Emory University, Atlanta, GA; and the Central Fulton Community Mental Health Center, Grady Health Systems, 60 Coca-Cola Place, Atlanta, GA. Address correspondence and reprint requests to Dr. Schwartz, Psychiatry, Grady Memorial Hospital, 80 Jesse Jill Jr. Dr., P.O. Box 26238, Atlanta, GA 30303. e-mail: aschwa2{at}emory.edu

The relationship of analgesic medication use with posttraumatic stress disorder (PTSD) diagnosis was investigated among a sample of 173 African Americans presenting for routine outpatient visits at an urban mental health center. Seventy-eight (43.5%) of the sample met DSM-IV PTSD criteria. Those with PTSD had significantly higher use of analgesic medication (both opiate and non-opiate), as compared with non-PTSD patients. PTSD symptoms, as measured by the Posttraumatic Symptom Scale, were significantly higher in subjects who were prescribed analgesics. The authors conclude that there may be a relationship between PTSD and use of pain medications warranting further examination of the endogenous opiate system in the pathophysiology of PTSD.

Key Words: Posttraumatic Stress Disorder • Pain Medication




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