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Psychosomatics 46:131-134, April 2005
© 2005 The Academy of Psychosomatic Medicine

Predictive Value of the CES-D in Detecting Depression Among Candidates for Disease-Modifying Multiple Sclerosis Treatment

Rupang Pandya, B.Sc., M.D., Luanne Metz, M.D., F.R.C.P.(C), and Scott B. Patten, M.D., F.R.C.P.(C), Ph.D.

Received July 21, 2003; revision received March 29, 2004; accepted May 12, 2004. From the Departments of Psychiatry, Clinical Neurosciences, and Community Health Sciences, University of Calgary; and the Alberta Heritage Foundation for Medical Research, Calgary. Address correspondence and reprint requests to Dr. Pandya, Psychiatry Administration, Department of Psychiatry, University of Calgary, 1403 29th St., NW, Calgary, ALB T3H 2R9, Canada; ruppandya{at}hotmail.com (e-mail).

The presence of depression is an important concern for patients with multiple sclerosis who are candidates for disease-modifying treatment, since depression may affect treatment adherence. The authors evaluated the positive predictive value of the Center for Epidemiologic Studies Depression Rating Scale (CES-D) in detecting depression among patients who were candidates for disease-modifying multiple sclerosis treatment. Of 47 patients who scored ≥16 on the CES-D, 74.5% (N=38) were found to have a depressive disorder. The results of the study indicate that case-finding for depressive disorders among multiple sclerosis patients can be facilitated by use of the CES-D scale.

Key Words: Major Depression • Depressive Disorder • Multiple Sclerosis • Psychiatric Symptom Rating Scales




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