Psychosomatics 42:411-415, October 2001
© 2001 The Academy of Psychosomatic Medicine
Psychiatric Comorbidity Among Hepatitis C-Positive Patients
Sonia P. Yovtcheva, M.D., M. Sc.,
Muhamad Aly Rifai, M.D.,
James K. Moles, M.D., and
Brian J. Van Der Linden, M.D., M.P.H.
Received December 22, 2000; revised May 11, 2001; accepted May 16, 2001. From the Department of Psychiatry, University of Virginia/Roanoke-Salem Psychiatric Medicine Program, and the Departments of Psychiatry and Gastroenterology, VA Medical Center, Salem, VA. Address correspondence and reprint requests to Dr. Rifai, University of Virginia, School of Medicine, VAMC 116A7, Salem, VA 24153. E-mail: mar4n{at}virginia.edu
This study assessed the prevalence of psychiatric disorders among hepatitis C patients at a Veterans Affairs Medical Center. Medical records of 306 randomly selected hepatitis C-positive patients were reviewed for past and present DSM-IV-based psychiatric disorders. Each psychiatric diagnosis was independently confirmed with DSM-IV criteria using symptoms recorded in the chart. Only independently confirmed diagnoses were included for analysis. Mood disorders were present in 38% of patients; personality disorders in 30%; PTSD in 19%; other anxiety disorders in 9%; and psychotic disorders in 17%. Although alcohol use disorders were found in 86% of this patient population, intravenous drug use disorders were present in only 28%. Our data indicate that prevalence rates of a variety of psychiatric disorders are higher in veterans with hepatitis C than in the general population. Mood, anxiety, personality, and psychotic disorders were all relatively common in these patients. Psychiatric disorders may influence the course and treatment of hepatitis C infection, and psychiatrists as well as internists should be aware of the substantial psychiatric comorbidity in patients with this infection.
Key Words: Psychiatric Disorders • Substance Abuse • Hepatitis C
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