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Neuropsychiatric Aspects of Parkinson's Disease

Received and accepted September 2, 1999. From the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland. Address correspondence and reprint requests to Dr. Marsh, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Meyer 3–166, Baltimore, MD 21287; e-mail: lmarsh{at}hmi.edu

Parkinson's disease (PD), a disorder characterized by movement abnormalities, is frequently complicated by psychiatric syndromes. Psychiatric assessment of the PD patient requires familiarity with the motor and cognitive aspects of PD, the various effects of antiparkinsonian medications, and how these relate to mental status changes and psychiatric phenomena. This review describes the various motor and nonmotor features of PD and focuses on the differential diagnosis of affective disorders in PD and their treatment.

Key Words: Neuropsychiatry • Parkinson's Disease • Basal Ganglia

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