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Depression in Pediatric Chronic Illness

A Diathesis-Stress Model

Received August 20, 1997; revised May 8, 1998; accepted May 18, 1998. From the Department of Psychiatry, University of Arizona Health Sciences Center, Tucson, Arizona. Address correspondence and reprint requests to Dr. Burke, Department of Psychiatry, University of Arizona Health Sciences Center, P.O. Box 245002, Tucson, AZ 85724–5002. e-mail: burke{at}u.arizona.edu

Depression in pediatric chronic illness has been receiving increasing attention in recent years. Studies to date have typically focused on characteristics of illness as the major determinants of the development of depression, but characteristics of the child have received less attention. This review suggests that a diathesis-stress model can be a fruitful heuristic that would incorporate illness characteristics and attributes of the child and environmental effects in an overall framework to guide future research and treatment.

Key Words: Depression • Children • Stress

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