Caffeine-withdrawal headache: A clinical profile

¹ Medical director of the Clinical Studies Unit Inpatient Program and director of neural and behavioral sciences at the University of Michigan Medical Center
² Medical students
³ Department of family practice of the University of Minnesota Hospitals

Caffeine withdrawal is an important but often overlooked cause of headache. In an ongoing investigation of caffeinism the authors used a questionnaire to determine whether there is a constellation of psychiatric characteristics associated with this type of headache. They found that persons who are susceptible to the syndrome generally report more symptoms of anxiety and depression and rate higher in tests evaluating those parameters; consume more antianxiety agents; feel they are less healthy; and have a significantly higher caffeine intake than persons without caffeine-withdrawal headaches.

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